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After smoking a cigarette, nicotine and its by-products stay in a person’s urine and saliva for 4 days and blood for up to 10 days. In this article, we look at whether this differs between smoking and vaping, what withdrawal feels like, and if people can affect how long it takes to clear their system of nicotine.

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Researchers have designed a drug that may soon be a safe, effective alternative to opioids for treating moderate-to-severe chronic pain.

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Medullary thyroid cancer (MTC) is a rare type of thyroid cancer. The earliest sign of MTC is typically a painless lump in the neck. Later symptoms can include pain or discomfort, hoarseness, coughing, and difficulty swallowing or breathing. If caught early, the outlook for MTC is often very good. Learn more here.

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Detrol LA (Tolterodine) reduces spasms of the bladder muscles. Tolterodine is used to treat overactive bladder with symptoms of urinary frequency, urgency, and incontinence. Tolterodine may also be used for purposes not listed in this medication guide.

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DETROL LA Capsules contain tolterodine tartrate. The active moiety, tolterodine, is a muscarinic receptor antagonist. Tolterodine tartrate is a white, crystalline powder with a molecular weight of 475.6. The pKa value is 9.87 and the solubility in water is 12 mg/mL. It is soluble in methanol, slightly soluble in ethanol, and practically insoluble in toluene. The partition coefficient (Log D) between n-octanol and water is 1.83 at pH 7.3. DETROL LA 4 mg capsule for oral administration contains 4 mg of tolterodine tartrate. Inactive ingredients are sucrose, starch, hypromellose, ethylcellulose, medium chain triglycerides, oleic acid, gelatin, and FD&C Blue #2. DETROL LA 2 mg capsule for oral administration contains 2 mg of tolterodine tartrate, and the following inactive ingredients: sucrose, starch, hypromellose, ethylcellulose, medium chain triglycerides, oleic acid, gelatin, yellow iron oxide, and FD&C Blue #2. Both the 2 mg and 4 mg capsule strengths are imprinted with a pharmaceutical grade printing ink that contains shellac glaze, titanium dioxide, propylene glycol, and simethicone.

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