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REMERON (mirtazapine) is most commonly used to treat depression. Mirtazapine is available in the United States under the trade names of REMERON and REMERON SolTab.

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REMERON (mirtazapine) is best known for treating depression. However, it may also be used for treating anxiety or to make people drowsy just before surgery.

Mirtazapine is usually thought of as an antidepressant, or a drug that alleviates symptoms of depression. Approved by the Federal Drug Administration (FDA) in 1996, it is believed to alter the activities of some chemicals in the brain and, in this way, reduce chemical imbalances responsible for causing depression and anxiety. As with all antidepressants, it may take several weeks of treatment before full beneficial effects are seen. Mirtazapine is broken down by the liver and eliminated from the body mostly by the kidneys. It is supplied in 15-, 30-, and 45-mg tablets.

The recommended initial dose of REMERON (mirtazapine) in 15 mg taken at bedtime. The dose may be increased in 15-mg increments every one or two weeks as needed until symptoms of depression or anxiety resolve. Typical doses range between 15 and 45 mg. Dosages above 45 mg per day are not recommended. Elderly people or those with liver or kidney disease should use mirtazapine carefully, since they may be more sensitive to some of the drug's side effects.

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